GCDH

A gene on chromosome 19p13.2 that encodes glutaryl-CoA dehydrogenase, a member of the acyl-CoA dehydrogenase family, which catalyses the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO2 in the degradative pathway of L-lysine, L-hydroxylysine and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor.

Molecular pathology
Defects in GCDH cause glutaric aciduria type 1.

Mentioned in

glutaryl-CoA dehydrogenase

References in periodicals archive

Assignment of human glutaryl-CoA dehydrogenase gene (GCDH) to the short arm of chromosome 19 (19p13.2) by in situ hybridization and somatic cell hybrid analysis.

Bilateral temporal arachnoid cysts and glutaric aciduria type 1/iki tarafli temporal araknoid kistler ve glutarik asiduri tip 1

4.2.1.2), General Proteins (GP), Glucose Dehydrogenase (GCDH, E.C.

Postglacial range fluctuation, genetic subdivision and speciation in the western North American spotted frog complex, Rana pretiosa

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