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furanocoumarin

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furanocoumarin

(fyūr-a-nō-kū-mah'rinz),
Member of a group of chemical compounds found in grapefruit, which includes bergamottin and 6'7'-dihydroxybergamottin. Inhibit CYP450 3A4, particularly in the GI tract.
See also: bergamottin.
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References in periodicals archive
There are many phytochemical studies on Heracleum species that mainly focused on furanocoumarins (8,9) and furanocoumarin glycosides, (10,11) together with alkaloids, (12) polyacetylenes, (13) and flavonoids.
Zangerl, "Adaptive significance of furanocoumarin diversity in Pastinaca sativa (Apiaceae)," Journal of Chemical Ecology, vol.
Honda et al., "Chemical constituents of Prangos tschimganica; structure elucidation and Butylisocoumarins absolute configuration of coumarin and furanocoumarin derivatives with anti-HIV activity," Chemical & Pharmaceutical Bulletin, vol.
Effect of maturity, processing, and storage on the furanocoumarin composition of grapefruit and grapefruit juice.
Leaves and stalks of celery contain phenols, furanocoumarin, psoralen, bergapten, fully and xanthotoxin that their amount is changing from 12 to 50 mg/kg [13].
The linear furanocoumarin imperatorin and the coumarin osthole extracted from Cnidium monnieri (L.) Cusson fruit were effective against larvae of Culex pipiens pallens Coquillett and Ae.
(24.) Guo LQ, Fukuda K, Ohta T, Yamazoe Y: Role of furanocoumarin derivatives on grapefruit j uice-mediated inhibition of human CYP3A activity.
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