References in periodicals archive

These molecular subtypes showed different gene expressions: the Uro subtype expressed FGFR3 and cyclin D1 (CCND1), with the frequent loss of 9p21 (cyclin-dependent kinase inhibitor 2A [CDKN2A]); the genomically unstable subtype expressed Forkhead box Ml (FOXM1) but not CK5, with the loss of RB1; and the basal/SCCL subtype expressed CK5 and CK14, but not FOXA1 and GATA-binding protein 3 (GATA3).

The essential pioneer factor FOXA1 will be the initial target as it has shown to be pivotal in the tumour development and maintenance of oestrogen-receptor positive luminal breast cancer.

Azeria Therapeutics raises GBP4m in Series A fundraising

(12) The genes that are most frequently associated with neuroendocrine carcinoma are GATA3, FOXA1, TBX3, and ARID1A as well as PIK3CA, AKT1, and CDH1.12 Genomic analysis of the liver lesion noted on progression of palbociclib-based treatment revealed that she had ESR1 Y537S and ARID1A L1915fs*3 mutations as well as CCND1 amplification.

Dramatic response to cyclin D-dependent kinase 4/6 inhibitor in refractory poorly differentiated neuroendocrine carcinoma of the breast

Specifically, HER2/MAPK kinase signaling activates E2F transcription factors, leading to the transcription of CCND1 gene encoding cyclin D1, while active estrogen receptor alpha (ER[alpha]) in complexwith FOXA1 transcription factor intensifies CCND1 transcription through an estradiol-responsive enhancer [85].

Overcoming Therapeutic Resistance of Triple Positive Breast Cancer with CDK4/6 Inhibition

Huang, "Modulation of androgen receptor by FoxA1 and FoxO1 factors in prostate cancer," International Journal of Biological Sciences, vol.

Genome-Wide Identification and Characterization of Fox Genes in the Honeybee, Apis cerana, and Comparative Analysis with Other Bee Fox Genes

Also, deletion of FOXA1 and FOXA2 in embryonic DA neurons affects the binding of NURR1 to the promoter region of TH and aromatic L-amino acid decarboxylase (AADC) genes leading to a significant loss of TH and AADC expression in the SNpc of embryos and adult mice [15].

Identification of NURR1 (Exon 4) and FOXA1 (Exon 3) Haplotypes Associated with mRNA Expression Levels in Peripheral Blood Lymphocytes of Parkinson's Patients in Small Indian Population

Additionally, gland development related terms included CAV1, homeobox A3 (HOXA3), E74-like factor 3 (ELF3), forkhead box A1 (FOXA1), homeobox A9 (HOXA9) genes as shown in Supplementary Table S2.

Characterizing milk production related genes in Holstein using RNA-seq

This group of genes produces transcripts that are related to pluripotency (OCT4 and SOX2), a transcription factor involved in morphogenesis and a homeobox family member (HOXD8), a regulator of development (SOX17), a replicative senescence controller (CDKN2A), and a transcription factor related to embryonic development (FOXA1).

DNA methylation patterns of candidate genes regulated by thymine DNA glycosylase in patients with TP53 germline mutations