eflornithine

[ef-lor´nĭ-thēn″]

an inhibitor of the enzyme catalyzing the decarboxylation of ornithine; used topically as the hydrochloride salt to reduce unwanted facial hair in females. It has also been administered intravenously in treatment of African trypanosomiasis.

eflornithine

An antiprotozoal drug used to treat Pneumocystis carinii pneumonia and African TRYPANOSOMIASIS. The drug is on the WHO official list.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

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References in periodicals archive

Keywords: Eflornithine, intense pulsed light, hirsutism.

A randomized study of eflornithine cream combined with intense pulsed light versus intense pulsed light treatment alone for hirsutism in women

Many different treatment modalities are available for the management of hirsutism in PCOS including non-pharmacological and pharmacological therapies like eflornithine OCPs, metformin, cyproterone acetate, and spironolactone.

COMPARISON OF EFFICACY OF SPIRONOLACTONE PLUS ORAL CONTRACEPTIVES WITH METFORMIN IN PATIENTS OF PCOS WITH HIRSUTISM

"We do cover eflornithine, but there is a problem ..."

Typhoid isn't covered??!!

The World Health Organization (WHO) and China CDC helped obtain nifurtimox and eflornithine, which we administered to the patient within 48 h after the diagnosis.

Human African Trypanosomiasis in Emigrant Returning to China from Gabon, 2017

Eflornithine cream is an FDA category C drug for use in pregnancy.

Preconception management of endocrine disorders

A quarter of the female patients in the study were treated with eflornithine hydrochloride, which inhibits hair cell growth, while fewer than 2% of males received this treatment.

Hormones loom large in female pseudofolliculitis barbae

Cyclosporine, Cycloserine, Eflornithine, Everolimus, Histrelin,

Repurposing - finding new uses for old (and patented) drugs: bridging the "Valley of Death," to translate academic research into new medicines

Eflornithine hydrochloride (Vaniqa) may also help slow the hair growth on the face.

Polycystic ovary syndrome

This combination consisted of sulindac, which is an older, established antiinflammatory medication, and [alpha]-difluoromethylornithine (DFMO), or eflornithine, a failed cancer-therapeutic drug that was later found to be a highly effective depilatory.

Cancer chemoprevention: successes and failures