Medical

familial expansile osteolysis

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familial expansile osteolysis

A rare autosomal dominant bone disorder (OMIM:174810) characterised by foci of increased bone remodelling, especially in the long bones beginning in early adulthood, often associated with early-onset deafness and loss of dentition.

Molecular pathology
Defects in TNFRSF11A, which encodes a member of the TNF receptor family essential for RANKL-mediated osteoclastogenesis, cause familial expansile osteolysis.
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References in periodicals archive
(9) Given the type of missions we expected to conduct in the 1990's, EOF was seen as a useful tool in self-defense situations where there was no declared hostile force or dedicated enemy.
A benefit of the new EOF design was the use of exhaust gases to preheat the steel substrate (e.g., scrap) materials before they were introduced into the melt vessel.
The concurrent Town of Islip predator and hard clam data sets (1992-2003, Table l) were analyzed for spatial and temporal trends using an EOF procedure, which partitioned the variance of the data into modes that represent space patterns with distinct time history.
The aim was to identify a suitable background electrolyte composition based on the use of these salts in different organic solvents and to investigate the effect of a background electrolyte on the EOF, as well as the actual mobilities of analytes using these background electrolytes.
The EOF was created in 1968 to support educationally and economically disadvantaged students for undergraduate, graduate and professional study at public and independent higher education institutions.
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