chromoblastomycosis

chromoblastomycosis

 [kro″mo-blas″to-mi-ko´sis]

a chronic fungal infection of the skin, usually beginning at the site of a puncture wound or other trauma on one leg or foot, but sometimes involving other areas of the body, with wartlike nodules or papillomas that may or may not ulcerate. It is usually caused by Phialophora verrucosa, Fonsecaea compactum, F. pedrosoi, or Cladosporium carrionii. Called also chromomycosis and verrucose or verrucous dermatitis.

Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

chro·mo·blas·to·my·co·sis

(krō'mō-blas'tō-mī-kō'sis),

A localized chronic mycosis of the skin and subcutaneous tissues characterized by skin lesions so rough and irregular as to present a cauliflowerlike appearance; caused by dematiaceous fungi such as Phialophora verrucosa, Exophiala (Wangiella) dermatitidis, Fonsecaea pedrosoi, F. compacta, and Cladosporium carrionii; fungal cells resembling copper pennies form rounded sclerotic bodies in tissue, with epidermal hyperplasia and intraepidermal microabscesses.

Synonym(s): chromomycosis

[chromo- + G. blastos, germ, + mykē, fungus, + -osis, condition]

Farlex Partner Medical Dictionary © Farlex 2012

blastomycosis

A suppurative granulomatous infection caused by Blastomyces dermatitidis which may disseminate from an inoculation site—cut, bruise or scrape—leaving a central scar, mimicking skin cancer.
 
At risk
Immunocompromised patients—e.g., with AIDS—are at increased risk for disseminated blastomycosis.

Epidemiology
± 4/100,000 symptomatic, many more asymptomatic.
 
Clinical-systemic
Usually acquired by inhalation, may produce dermatitis, pneumonitis or present as a systemic disease in the skin, lungs, bones, liver, spleen or CNS. Usually begins as a respiratory infection, accompanied by cough, pleuritic chest pain, adult respiratory distress syndrome (ARDS), chills, malaise, anorexia and/or weight loss.

Management
Amphotericin B, especially for immunocompromised patients; itraconazole is the drug of choice for nonlife-threatening, non-CNS blastomycosis.

Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

chromoblastomycosis

Chromomycosis Infectious disease An infection by various dematiaceous fungi: Fonsecaea pedrosoi, F compacta, Phialophora verrucosa, Cladosporium carrionii, Rhinocladiella aquaspersa Epidemiology Most US infections occur in whites, age 30–50, who are farmers or manual laborers Clinical Verrucoid, ulcerated, crusted lesions with pseudoepitheliomatous hyperplasia, keratolytic microabscesses. Cf Blastomycosis, Phaeohyphomycosis.

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

chro·mo·blas·to·my·co·sis

(krō'mō-blas'tō-mī-kō'sis)

A localized chronic mycosis of the skin and subcutaneous tissues characterized by skin lesions so rough and irregular as to present a cauliflowerlike appearance; caused by dematiaceous fungi such as Phialophora verrucosa, P. dermatitidis, Fonsecaea pedrosoi, F. compacta, and Cladophialophora carrionii; fungal cells resembling pennies form rounded sclerotic bodies in tissue, with epidermal hyperplasia and intraepidermal microabscesses.
Synonym(s): chromomycosis.

[chromo- + G. blastos, germ, + mykē, fungus, + -osis, condition]

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

chromoblastomycosis

A deep fungus tropical infection of the skin, usually on the foot, caused by a variety of fungi, and acquired on splinters of decaying wood. There are warty nodules that may ulcerate. The condition is very persistent. It is also known as chromomycosis.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005