(10.) Moore C, Rana S, Coulter C Simultaneous identification of 2-carboxy-tetrahydrocannabinol, tetrahydrocannabinol,
cannabinol and cannabidiol in oral fluid.
Potency trends of [delta] 9 -tetrahydrocannabinol, cannabidiol and
cannabinol in cannabis in the Netherlands: 2005-15.
The cannabinoids species more abundant detected are
cannabinol (CBN), cannabitriol (CBT) and [[DELTA].sup.9]-THCA.
See also l DAVID EVANS, DRUG TESTING LAW, TECHNOLOGY & PRACTICE [section] 1:19 (West 2017) (noting "[m]arijuana contains 500 chemicals including over 100 compounds called cannabinoids, including
cannabinol, cannabidiol, cannabinolidic acids, cannabigerol, cannabichromene, and several isomers of tetrahydrocannabinol (THC)").
The plant contains toxins; the most important ones of them are tetrahydrocannabinol, cannabidiol, and
cannabinol. This is why it belongs to the category of toxic plants of therapeutic interest.
The signals were optimized using a source block temperature of 500[degrees]C and an on-spray in the determination of [[DELTA].sup.9]-tetrahydrocannabinol, cannabidiol, and
cannabinol in 50 mg of 179 hair samples.
Among the other cannabinoids, the most studied ones are dronabinol (DBN) and nabilone, followed by
cannabinol (CBN), cannabidiol (CBD), which seems to possess some anti-inflammatory, analgesic (Hohmann & Suplita, 2006; Rea, Roche & Finn, 2007; Jhaveri et al, 2008), anti-schemic (Lamontagne et al, 2006), antipsychotic (Leweke, Koethe & Gerth, 2005), ansiolitic (Crippa et al, 2011), and anti-epileptic effects (Mortati, Dworetzky & Devinsky, 2007); and finally, cannabigerol (CBG) and cannabicromeno (CBC) (Barceloux, 2012), which possess some properties which have been studied mainly in preclinical or animal models.
The research component of this special report is highly significant and a crucial contribution to the field, as it is designed to fill 2 voids: to compare blood and oral fluid THC, CBD,
cannabinol (CBN), and metabolite concentrations following ingestion of edibles laced with cannabinoids; and to compare roadside testing devices that monitor oral fluids for cannabinoids with standard analytical techniques (LC-MS/MS), following consumption of cannabinoid edibles.
Furthermore, CYP2C9 inhibition was demonstrated in-vitro for THC, CBD and
cannabinol (CBN) in Cannabis smoke.