C-cell hyperplasia

An increase in the size and function of the para-follicular cells of the thyroid, which is a precursor lesion of the familial (MEN 1, MEN2a, MEN 2) thyroid syndromes.

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References in periodicals archive

C-cell hyperplasia is divided into reactive or physiologic CCH and neoplastic CCH.

C-cell hyperplasia in multiple endocrine neoplasia 2A has demonstrated monoclonality, down-regulated apoptosis, and tumor-suppressor gene abnormalities consistent with intraepithelial neoplasia.

C-cell hyperplasia associated with chronic lymphocytic thyroiditis: a retrospective quantitative study of 112 cases.

C Cell and Follicular Epithelial Cell Precursor Lesions of the Thyroid

Physiologic versus neoplastic C-cell hyperplasia of the thyroid: separation of distinct histologic and biologic entities.

Five Top Stories in Thyroid Pathology

This variability, particularly at low CT concentrations, led to the recommendation to use reliable and sensitive assays in the screening of MTC and C-cell hyperplasia (1).

Comparison of calcitonin determinations by polyclonal and monoclonal IRMAs

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