Buruli ulcer. Review of a neglected skin mycobacterial disease.
[6] World Health Organization,
Buruli ulcer: Number of New Cases of
Buruli Ulcer Reported (Per Year), WHO, Geneva, Switzerland, 2011, http://apps.who.int/neglected_diseases/ntddata/buruli/buruli.html.
Comparison of features of leprosy and
Buruli ulcer (BU) Leprosy Characteristic Geography In > 90 countries (especially Brazil, India, Indonesia, Nepal) Epidemiology 2nd most common human mycobacterial disease Reported 2013 > 200,000 cases on treatment > 200,000 new cases diagnosed Underreporting Yes Organism M.
Ake et al., "
Buruli ulcer in Liberia, 2012," Emerging Infectious Diseases, vol.
We observed a total cicatrization of
Buruli ulcer lesions (Figure 2) and stopped the antimycobacterial treatment.
Protective efficacy of a DNA vaccine encoding antigen 85A from Myocobacterium bovis BCG against
buruli ulcer. Infect.
Earlier epidemiological reports showed that
Buruli ulcer outbreaks often occur near such still waters in the tropics.
Two debilitating diseases,
Buruli ulcer and Guinea worm, have received special attention under the fund.
Buruli ulcer is a bacterial infection which gets under the skin and spreads until it falls off, leaving sufferers with whole areas of their legs exposed, often needing amputation.
The team will bring 100 pieces of postcard-sized cultured skin to the Ghana capital of Accra, where they will treat
Buruli ulcer patients, since there is no equipment to cultivate skin in the west African country.
ALM is evolving its mission with a program that is code-named "Leprosy Plus," by identifying new diseases related or similar to leprosy, such as the
Buruli ulcer. This is the flesh-eating, bacteria-borne disease that has recently made world-wide headlines.