An X-linked dysmorphia complex [MIM 312870] which is characterised by a large, square protruding jaw, a broad nasal bridge, an upturned nose tip, and macroglossia, resulting in a physiognomy fancifully likened to that of a bulldog, and broad short hands and feet, occasionally with polydactyly, and other defects including pectus excavatum, ventricular septal defect (or other congenital heart defects), Meckel diverticulum, intestinal malrotation, and congenital diaphragmatic hernia, and paediatric tumours, e.g., Wilms tumour, neuroblastoma

Simpson,

J.L., U.S. physician.

Simpson syndrome - X-linked dysmorphia syndrome. Synonym(s): bulldog syndrome

Medical Eponyms © Farlex 2012

Mentioned in

References in periodicals archive

Also called as Bulldog Syndrome, DGSX Golabi- Rosen Syndrome, Dysplasia Gigantism Syndrome, X-Linked SDYS, SGB Syndrome, Simpson-Golabi- Behmel Syndrome Simpson dysmorphia syndrome types 1 and 2 are two forms of a rare, X-linked recessive, inherited disorder characterized by unusually large fetuses (prenatal overgrowth) and unusually large babies (postnatal overgrowth).

Syndrome associated with cleft palate and cleft lip

All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.