Bisphosphonates include Aclasta, Actonel, Aredia,
Bondronat, Boniva, Didronel, Fosamax, Fosavance, Reclast, Skelid and Zometa.
Recently announced data show that Bondronat (ibandronic acid) administered for the treatment of metastatic bone disease for 15 minutes has a safety profile consistent with the same dose of the drug administered during an hour.
Once approved as a 15 minute infusion, Bondronat will be the only bisphosphonate available in both short IV and oral formulations, and will thus offer a new consistency of care in the management of this devastating disease." For further information about Bondronat, please visit www.rocheuk.com.
Bondronat, made by Roche, is used to treat breast cancer which has spread to the bone -also known as metastatic bone disease.
Bondronat can be taken as a pill, meaning that patients can manage their treatment without having to go into hospital.
Bondronat, made by Roche, is used to treat breast cancer which has spread to the bone - also known as metastatic bone disease.
Bondronat can be taken as a pill, so patients can manage treatment without going into hospital.
The arrival of
Bondronat, made by Roche, was welcomed by campaigners and doctors.
Among the most promising prospects are CERA (Continuous Erythropoiesis Receptor Activator) for anemia, Bondronat for osteoporosis, the still-unnamed R450 for stress urinary incontinence (most common in women) and MRA for rheumatoid arthritis.
In Roche's Pipeline Human Drug Name Condition Research Stage (Subsidiary or alliance company in parenthesis) Bondronat Osteoporosis Tests completed; awaiting federal approval Avastin (Genentech) Colorectal cancer Late-stage tests Pemtumomab (Antisoma) Ovarian cancer Late-stage CERA Anemia Mid-stage Diflomotecan Colorectal, lung, Mid-stage (Beaufour Ipsen) and breast cancer MRA (Chugai) Rheumatoid arthritis Mid-stage NK1 Depression Mid-stage VCAM Asthma Mid-stage [R.sub.45[degrees]] Stress urinary Mid-stage incontinence TheraFab (Antisoma) Cancer Early-stage Therex (Antisoma) Cancer Early-stage DMXAA (Antisoma) Cancer Early-stage Source: Roche