A proprietary—CryoLife—adhesive used to repair aortic dissections, seal vessels, and reconstruct and reinforce peribronchial soft tissue to decrease air leaks
Composition Bovine serum albumin and glutaraldehydeare dispensed via a double-chambered syringe. Once dispensed, the adhesive components mix within the applicator tip where the cross-linking begins (within 20 to 30 seconds; it reaches bond strength within 2 minutes). The glutaraldehyde molecules bond with the BSA molecules creating a flexible mechanical seal independent of the body's clotting mechanism.

References in periodicals archive

There are many types of HAs and glues, such as gelatine matrix thrombin tissue sealant (FloSeal; Baxter Healthcare, Deerfield, IL, USA), fibrin glue (Tisseel; Baxter), bovine serum albumin-based adhesive (BioGlue; CryoLife, Keeensaw, GA, USA), and cyanoacrylate glue (Glubran; General Enterprise Marketing, Viareggio, Lucca, Italy).

A Modified Surgical Technique Using Cyanoacrylate Glue and Parenchymal Restoration Sutures without Tissue Approximation in Patients with Renal Tumors Who Underwent Open Partial Nephrectomy/Acik Parsiyel Nefrektomi Uygulanan Bobrek Tumorlu Hastalarda Doku Yaklastirilmasi Yapilmadan Siyanoakrilat Glue ve Prankimal Restorasyon Suturleri Kullanilarak Yapilan Modifiye Cerrahi Teknik

Harvard University scientists have created a socalled bioglue, based on the mucus secreted by slugs which, they claim, is very strong and sticks even in very moist situations.

The creepy-crawlies that could boost your health

The increase was driven by strong revenue growth from JOTEC, On-X and BioGlue.

CryoLife incurs lower net loss of USD297,000 for Q1 2019

Cerebrospinal fluid leak rate after the use of BioGlue in translabyrinthine vestibular schwannoma surgery: a prospective study.

Eustachian Tube Obliteration and its Effect on Rhinoliquorrhea in Translabyrinthine Vestibular Schwannoma Excision

BioGlue (25% bovine serum albumin and 10% glutaraldehyde; Cryolife Inc., Kennesaw, GA, USA) was approved by the FDA in 1998 for surgical application and is utilized in cardiovascular and pulmonary surgery, that is, for application during aortic root reconstruction and valve placement as well as for control of alveolar air leaks [21, 22].

Bovine Serum Albumin-Glutaraldehyde Sealed Fish-Mouth Closure of the Pancreatic Remnant during Distal Pancreatectomy

Treatment of splenic injury during laparoscopic nephrectomy with BioGlue, a surgical adhesive.

Experience with sliding-clip splenorrhaphy for splenic injury during radical nephrectomy

To prevent bleeding, BioGlue is used to seal the anastomosis.

Modification of the HeRO graft allowing earlier cannulation and reduction in catheter dependent days in patients with end stage renal disease: a single center retrospective review

The abnormal diaphragmatic surface was sealed with bioglue, and a vascularized parietal pleural flap was created and tacked over the diaphragm with permanent suture (Figure 4).

Bronchobiliary fistula: a case report

CryoLife, Inc, Atlanta, GA, announced that its BioGlue Surgical Adhesive has received Shonin approval from the Japanese Ministry of Health, Labor and Welfare (MHLW) for use in the repair of aortic dissections.

CryoLife receives Japanese regulatory approval to distribute BioGlue Surgical Adhesive

With the help of micro-manipulation technique, the researchers measured the force needed to overcome the bioglue adhesion, and showed that dried biofilm stuck 20-times more tightly than fresh biofilm.

Serratia bacteria can help build durable bone implants