Bac·te·roi·des frag·'i·lis

a bacterial species found in human and animal intestinal tracts. Although it represents only about 10-20% of Bacteroides species found in the colon, it is the primary species associated with intraabdominal abscesses and other subdiaphragmatic infections in humans, including peritonitis, rectal abscess, abdominal surgical wounds, and urogenital tract infection. Its capsule is capable of inducing abscess formation independently; characteristically, this species produces a β-lactamase that inactivates β-lactam antibiotics such as the penicillin and cephalosporin groups; it is the type species of the genus, Bacteroides.

Farlex Partner Medical Dictionary © Farlex 2012

Bacteroides fragilis

A gram-negative anaerobe which is a frequent isolate in anaerobic cultures; it is associated with abscesses, aspiration pneumonia, endocarditis, septic arthritis and empyema.

Bacteroides fragilis

Microbiology A gram-negative anaerobe which is a frequent isolate in anaerobic cultures; it is associated with abscesses, aspiration pneumonia, endocarditis, septic arthritis and empyema

Bac·te·roi·des frag·i·lis

(bak-tēr-oy'dēz fraj'i-lis)

A species that is one of the predominant organisms in the lower intestinal tract of humans and other animals; also found in specimens from appendicitis, peritonitis, rectal abscesses, pilonidal cysts, surgical wounds, and lesions of the urogenital tract. It is the type species of the genus Bacteroides.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

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References in periodicals archive

Specific bacterial antigens, such as PSA from Bacteroides fragilis, mediate the migration of the CNS, indicating a substantial interaction between the intestinal mucosa and the brain [69].

Does the Gut Microbiota Influence Immunity and Inflammation in Multiple Sclerosis Pathophysiology?

Cutaneous abscess below the waist have often been found to be caused by colonic flora anaerobes including Bacteroides fragilis.

Bacteroides fragilis in sepsis

Determinants of resistance in Bacteroides fragilis strains according to recent Brazilian profiles of antimicrobial susceptibility.

Clinically significant anaerobic bacteria isolated from patients in a South African academic hospital--antimicrobial susceptibility testing

coli, and Streptococci fecalis), anaerobic bacteria (Clostridium perfringens and Bacteroides fragilis), and fungal (Candida albicans) antigens.

ELISA tests for IgG/IgM gut flora immunity

In some cases, including the present case, the patients had a history of pelvic inflammatory disease.[12,18] In several cases bacteria, including Bacteroides fragilis, E coli, Proteus vulgaris, and Salmonella typhi grew from bacterial cultures.[12,13,20,22] Bacteria have also been associated with xanthogranulomatous inflammation in other organs[5,6,7,10,14] Escherichia coli was cultured from ovarian abscess fluid in the present case.

Xanthogranulomatous Salpingitis and Oophoritis: A Case Report and Review of the Literature

Zerbaxa used in combination with metronidazole is indicated in adult patients for the treatment of complicated intra-abdominal infections caused by the following Gram-negative and Gram-positive microorganisms: Enterobacter cloacae, Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Bacteroides fragilis, Streptococcus anginosus, Streptococcus constellatus, and Streptococcus salivarius.

FDA Accepts for Review New Drug Application for US Merck's Investigational Combination of Imipenem/Cilastatin and Relebactam, and Supplemental NDA for Zerbaxa (Ceftolozane and Tazobactam)

The presence of beneficial bacteria, such as Bifidobacterium longum, and a reduction in Bacteroides fragilis [31] in the gut have been associated with a lower incidence of asthma.

Early-Life Intestine Microbiota and Lung Health in Children

Separation of capsulate and non-capsulate Bacteroides fragilis on a discontinuous density gradient.

Streptococcus suis serotype 2 capsule in vivo

Staphylococcus aureus, Pseudomonas aeruginosa, Beta-hemolytic streptococci, Proteus species and Bacteroides fragilis. Several studies have been made of the peritoneal fluid and bacterial pattern of appendix fossa.

Bacterial pattern of appendix in acute and chronic appendicitis with its clinical correlation

Take a humble gut bacterium called Bacteroides fragilis. This species is ancient, at least 500 million years old, and has probably been living in the gut from humankind's beginning, says Caltech microbiologist Sarkis Mazmanian.

Inside job: teams of microbes pull strings in the human body