BMP5

A gene on chromosome 6p12.1 that encodes bone morphogenetic protein-5, which induces cartilage and bone formation, and is thought to act as a key signalling molecule within the trabecular meshwork of the eye and optic nerve head.

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References in periodicals archive

Association of a functional microsatellite within intron 1 of the BMP5 gene with susceptibility to osteoarthritis.

An investigation into the relationship between Taq1 and Apa1 polymorphisms of the vitamin D receptor gene and the development of osteoarthritis / osteoartrit gelisimi ve vitamin D reseptor geni TaqI ve ApaI polimorfizmleri arasindaki iliski uzerine bir arastlrma

These lncRNAs (AC078851.1, RP11-45A16.4, XLOC_002932, RP4-613B23.1, and RP11-305L7.6) and mRNAs (ALP, COL1A1, and COL1A20) are upregulated and BMP5 and IL6 are downregulated as verified by Q-PCR indicating that there are 131 pairs of lncRNA-mRNA regulatory relationships and 262 pairs of positive regulatory relationships, and MAPK, VEGF, and TGF-[beta] signaling pathways were mainly involved in the regulation during osteogenic differentiation process [47].

An Overview of Long Noncoding RNAs Involved in Bone Regeneration from Mesenchymal Stem Cells

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