anaphase promoting complex
Also found in: Encyclopedia, Wikipedia.(redirected from Anaphase-promoting complex)
anaphase promoting complex
A large protein complex of 11 to 13 proteins—including cullin (Apc2), RING (Apc11), and other proteins of as yet unknown functions—which is an E3 ubiquitin ligase that targets cell cycle proteins for degradation by the 26S proteasome.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive
Solomon, "The anaphase-promoting complex: it's not just for mitosis any more," Genes & Development, vol.
Peters, "Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons," Proceedings of the National Academy of Sciences of the United States of America, vol.
Kaplan, "The
anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C.
elegans, multiple ubiquitin ligases have been implicated in UPS-dependent regulation of AMPAR synaptic abundance, including the
anaphase-promoting complex (APC) [48], CUL3/KEL-8 [49], and RPM-1 [50].
Copyright © 2003-2025 Farlex, Inc
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.