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amodiaquine

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amodiaquine

 [am″o-di´ah-kwin]
an antimalarial, administered orally as the hydrochloride salt in the treatment of malaria, especially falciparum malaria.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
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References in periodicals archive
A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: Amodiaquine and sulphadoxine-pyrimethamine.
HISTOPATHOLOGICAL EFFECTS OF DIFFERENT ARTEMISININ DERIVATIVES ON LIVER OF MALE ALBINO MICE
Tahar et al., "Efficacy of sulfadoxine-pyrimethamine, amodiaquine, and sulfadoxine-pyrimethamine- amodiaquine combination for the treatment of uncomplicated falciparum malaria in the urban and suburban areas of Brazzaville (Congo)," Acta Tropica, vol.
Evaluation of Routine Microscopy Performance for Malaria Diagnosis at Three Different Health Centers in Brazzaville, Republic of Congo
Antimalarial drug regimens prescribed n (%) Non-artemisinin monotherapies (NAMTs) 8 (2.4) Proguanil 5 (1.5) Sulphadoxine-Pyrimethamine 2 (0.6) Amodiaquine 1 (0.3) Artemisinin monotherapies (AMTs) 6 (1.8) Artesunate 2 (0.6) Arteether 2 (0.6) Artemether 1 (0.3) Dihydroartemisinin 1 (0.3) Artemisinin combination therapies (ACTs) 319 (95.8) Artemether/Lumefantrine 269 (80.8) Artesunate/ Meflo quine 20 (6.0) Dihydroartemisinin/Piperaquine 16 (4.8) Artesunate/Amo diaquine 8 (2.4) Artesunate/Piperaquine 4(1.2) Artemether/Lumefantrine + Sulphadoxine-Pyrimethamine 1 (0.3) Artesunate/Sulphadoxine-Pyrimethamine + Proguanil 1 (0.3) Table 3: Drug prescribing indicators.
The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria
Keywords * Malaria * Chloroquine * Amodiaquine * Drug resistance
Introducing new antimalarial analogues of chloroquine and amodiaquine: A narrative review
Effects of co-administration of artesunate and amodiaquine on some cardiovascular disease indices in rats.
Artesunate attenuated progression of atherosclerosis lesion formation alone or combined with rosuvastatin through inhibition of pro-inflammatory cytokines and pro-inflammatory chemokines
There are several antimalarials targeting the blood forms of P vivax, such as chloroquine, amodiaquine, artesunate, artemether, lumefantrine, dihydroartemisinin, piperaquine, chloroquine remains the most widely used as first-line treatment for this species (2,7).
Therapeutic efficacy of alternative primaquine regimens to standard treatment in preventing relapses by Plasmodium vivax: a systematic review and meta-analysis/Eficacia terapeutica de esquemas de primaquina usados como alternativa al tratamiento estandar en la prevencion de recaidas por Plasmodium vivax: una revision sistematica y meta-analisis
falciparum malaria cases are artemether-lumefantrine (AM-LF), artesunatemefloquine (AS-MQ), artesunate-sulfadoxine-pyrimethamine (AS-SP), dihydroartemisinin-piperaquine, and artesunate amodiaquine (2).
Detection of point mutation in Plasmodium falciparum ATPase6 gene associated with artemisinin resistance from Assam and Arunachal Pradesh
Sanofi added that more than 1.7m treatments of its ArteSunate AmodiaQuine Winthrop (ASAQ Winthrop, which is a fixed dose artemisinin-based combination therapy) is being manufactured with semisynthetic artesunate in Morocco and are being shipped from its distribution centre to Burkina Faso, Burundi, Congo, Liberia, Niger and Nigeria.
Sanofi ships first antimalarial treatments produced with semisynthetic artemisinin to Africa, marking a critical step in improving access to treatment worldwide
Artemisinin with an endoperoxide sesquiterpene lactone structure is unlike those of any other known antimalarials (mefloquine, amodiaquine, and chloroquine) that kills all stages of the parasite by a reductive interaction with free heme, resulting in generation of some types of free radicals that could alkylate parasite proteins and damage membranes [8].
Evaluation of in vitro antimalarial activity of different extracts of Artemisia aucheri Boiss. and A. armeniaca Lam. and fractions of the most potent extracts
White, "Pharmacokinetics of quinine, chloroquine and amodiaquine: clinical implications," Clinical Pharmacokinetics, vol.
Recrudescence of Plasmodium malariae after quinine
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