Acid dissociation constants of ligands were computed from data which were obtained by potentiometric titrations using HYPERQUAD computer program.
In conclusion, the acid dissociation constants of thiohydantoin-pyrrolidine fused derivatives, which constitute important information for future studies in this area, were determined potentiometrically and the results were interpreted with the HYPERQUAD computer program.
de Amici, "Determination of acid dissociation constants of compounds active at neuronal nicotinic acetylcholine receptors by means of electrophoretic and potentiometric techniques," Analytical Sciences, vol.