demonstrated the activation of
Aldh1a2 in the endocardium and epicardium and showed that retinoic acid signaling is crucial for CM proliferation during zebrafish cardiac regeneration [221].
Bassil et al., "IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing
Aldh1a2," The Journal of Immunology, vol.
Linney et al., "Analysis of
ALDH1A2, CYP26A1, CYP26B1, CRABP1, and CRABP2 in human neural tube defects suggests a possible association with alleles in
ALDH1A2," Birth Defects Research A--Clinical and Molecular Teratology, vol.
Severe OA of the hand has been recently shown to associate with common variants within the
ALDH1A2 gene and with rare variants at 1p31 in Northern European Caucasians.
Lakhal-Chaieb et al., "A human
ALDH1A2 gene variant is associated with increased newborn kidney size and serum retinoic acid," Kidney International, vol.
Hair cycle-specific immunolocalization of retinoic acid synthesizing enzymes
Aldh1a2 and Aldh1a3 indicate complex regulation.