AGPAT1

A gene on chromosome 6p21.3 that encodes an enzyme which localises to the endoplasmic reticulum, where it converts lysophosphatidic acid into phosphatidic acid, both of which are involved in signal transduction and lipid biosynthesis.

References in periodicals archive

Stimulation of BMM was also associated with the upregulation of 1-acylglycerol-3-phosphate O-acyltransferase 1 (AGPAT1) and phosphatidate cytidylyltransferase 1 (CDS1), which may increase cytidine diphosphate- (CDP-) diacylglycerol production, a precursor for phosphatidylinositol, phosphatidylglycerol, and cardiolipin synthesis.

Transcriptional Profiling Suggests Extensive Metabolic Rewiring of Human and Mouse Macrophages during Early Interferon Alpha Responses

2012), Huntington's disease (H2AFY2, AGPAT1) (Cong et al.

Placental DNA methylation related to both infant toenail mercury and adverse neurobehavioral outcomes

The BMET array contains four genes of these isoforms, and AGPAT1 was the most abundant transcript in both tissues.

Gene expression profiling of liver and mammary tissues of lactating dairy cows

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