ACAD9

A gene on chromosome 3q21.3 that encodes a dehydrogenase three times more active on palmitoyl-CoA than on stearoyl-CoA. ACAD9 is ubiquitously expressed in most normal human tissues and cancer cell lines, especially in heart, skeletal muscles, brain, kidney and liver.

Molecular pathology
Defects in ACAD9 cause isobutyryl-CoA dehydrogenase deficiency.

Mentioned in

acyl-CoA dehydrogenase type-9 deficiency

References in periodicals archive

TTest analysis for these genes between the vehicle-exposed and the G-treated cells--at a significance level of 0.05--indicated that ACSL1, ABCA1, DHCR24, ACAT2, ACACA, ABCG1, ACAD9, ACACB, IDI1, PPARG, SCD, SCARB1, HMGCS1, EBP, DHCR7, FASN, HMGCR, and GPAM were down-regulated upon G treatment; whereas NR1H2, PPARA, INSIG2, CPTP1, APOE, VLDLR, ABCC2, and SREBF2 were activated after exposure to G (Fig.

Modulation by geraniol of gene expression involved in lipid metabolism leading to a reduction of serum-cholesterol and triglyceride levels

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