A224L
A224L
A structural protein belonging to the inhibitor of apoptosis protein (IAP) family, which is encoded by the African swine fever virus. Overexpression of A224L in Vero cells substantially inhibits the activity of caspase-3 and apoptotic cell death induced by TNF-alpha and cycloheximide or staurosporine.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive
In the early stages of infection, the early viral protein A238L inhibits NF-[kappa][beta] expression, but once the infection progresses the late viral protein
A224L stimulates its expression (60).
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