Medical

17-hydroxycorticosteroid

17-hydroxycorticosteroid

Any of the steroid hormones synthesized in the adrenal gland by action of 17-hydroxylase–cortisol, cortisone, 11-deoxycortisol and tetrahydro derivatives; urine excretion of 17-OHCSs is a rough guide of functional status of the adrenal gland and rate of catabolism ↑ in Pregnancy, Cushing's disease, obesity, pancreatitis ↓ in Addison's disease, hypopituitarism Ref range < age 1, 1.4-2.8 µmol/24–US: < 1 mg/24; adult 8.2-27.6 µmol/24–US: 3-11 mg/24
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
Screening test for Cushing's syndrome include 24-hour urine, free cortisol measurement, blood glucose measurement, 17-hydroxycorticosteroid and midnight serum cortisol concentrations, and the dexamethasone suppression test.
First, urinary 17-hydroxycorticosteroid 117 OHCS) level was measured which was normal (11.72 mg/day, normal: 9.00-22.00 mg/day).
Over 75% of patients achieve normal levels of urinary free cortisol and 17-hydroxycorticosteroid while on ketoconazole (Greenberg, 2001).
The historic 24-h 17-hydroxycorticosteroid test is not recommended as a screening test for Cushing syndrome because of low diagnostic accuracy (12).
A comparative study of urinary 17-hydroxycorticosteroids, urinary free cortisol, and the integrated concentration of plasma cortisol.
17-OHCS 17-hydroxycorticosteroid OM obtuse marginal (coronary
Finally, the book claims that high-dose dexamethasone suppression testing fails to decrease urinary 17-hydroxycorticosteroid production in Cushing disease.
The excretion of 17-hydroxycorticosteroids (17-OHCS) and 17-keto steroids (17-KS) in urine was 2.4 mg/day and 2.5 mg/day, respectively, both of which were below the normal ranges (2.6-7.8 mg/day and 3.1-8.8 mg/day, resp.).
Examples of physiological systems that have been reported to be affected include ACTH, oxytocin, vasopressin, norepinephrine, follicle stimulating hormone, prolactin, and 17-hydroxycorticosteroids, immune, and cardiovascular functions.
The serum adrenocorticotropic hormone (ACTH) level and urinary excretion of 17-hydroxycorticosteroids (OHCS) did not differ among the pregnant groups.
Urine measurement of excretion of 17-ketosteroids (17-KS) and 17-hydroxycorticosteroids (17-OHCS).
XII Myopathy due to the administration of therapeutic amounts of 17-Hydroxycorticosteroids. Am.
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