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Zinc Finger |
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zinc finger,
a loop of a transcription factor that is stabilized by a zinc atom linked to four carbon atoms in the protein. It is an important step in the cloning and sequencing of human general transcription factors because individual proteins appear to be involved in the regulation of transcription and in RNA transport. Zinc Finger A small tertiary protein structural motif of higher organisms, in which parts of a protein fold around a zinc molecule, acting as a hook to attach activator proteins to DNA; the ZF motif is present in many proteins that regulate expression of eukaryotic genes—e.g., proto-oncogenes, Wilms’ tumour gene, growth signal receptors Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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