ze·bra body (z  br )n. A granule found in Schwann cells and macrophages of individuals suffering from metachromatic leukodystrophy. |
Zebra Body
A descriptive term for a lysosome containing broad transversely-stacked myelinoid membranes, an ultrastructural finding typical of certain lysosomal storage diseases, found in neurons, Schwann cells, macrophages, smooth muscle cells, endothelial cells, pericytes, glomerular epithelial cells, hepatocytes, and other cells. Zebra bodies classically occur in Fabry’s disease, but are seen in Niemann-Pick disease, Landing’s disease, Sandhoff’s disease, mucopolysaccharidoses—e.g., Hurler syndrome—myelinopathy, phenylketonuria, and Tay-Sachs disease
Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
| ?Page tools | ||
|---|---|---|
|