ranitidine /ra·ni·ti·dine/ (rah-nĭ´tĭ-dēn) a histamine H2 receptor antagonist, used as the hydrochloride salt to inhibit gastric acid secretion in the treatment of gastric and duodenal ulcer, gastroesophageal reflux disease, and conditions that cause gastric hypersecretion.
ranitidine
ranitidine [rah-nit´ĭ-dēn]
ranitidine (r
nit´dēn´),
ranitidine
ra·nit·i·dine (r -n t -d n )n. An antagonist for one of two types of histamine receptors occurring on the surfaces of cells, especially gastric cells, that acts by inhibiting gastric acid secretion and is used in the treatment of duodenal ulcers. |
ranitidine
[ranit′idēn]
a histamine H2 receptor antagonist.
indications It is prescribed in the treatment of gastroesophageal reflux disease and gastric hypersecretory conditions.
contraindications Known sensitivity to this drug prohibits its use. The drug should be used in pregnancy only if clearly needed and with caution in those with severe hepatic or renal impairment.
adverse effects Among the most serious adverse effects are acquired hemolytic anemia, agranulocytosis, atrioventricular block, agitation, dizziness, headaches, rashes, gynecomastia, and loss of libido.
ranitidine [rah-nit´ĭ-dēn]
an antagonist of histamine H2receptors, used as the hydrochloride salt to inhibit stomach hydrochloric acid secretion in treatment of peptic ulcers, gastroesophageal reflux, and conditions of gastric hypersecretion, administered orally, intramuscularly, or intravenously.
ranitidine (r
nit´dēn´),n brand name: Zantac, Zantac EFFERdose, Zantac GELdose, Zantac 75;
drug class: H2-histamine receptor antagonist;
action: inhibits histamine at H2 receptor sites in parietal cells, which inhibit gastric acid secretion;
uses: duodenal ulcers, gastric ulcers, hypersecretory conditions, gastroesophageal reflux disease.
drug class: H2-histamine receptor antagonist;
action: inhibits histamine at H2 receptor sites in parietal cells, which inhibit gastric acid secretion;
uses: duodenal ulcers, gastric ulcers, hypersecretory conditions, gastroesophageal reflux disease.
ranitidine
a histamine H2-blocking agent used in the treatment of gastric ulceration and chronic hypertrophic gastritis.
ranitidine
Zantac™ Therapeutics An H2-receptor antagonist used to treat peptic ulcer disease, gastric and duodenal ulcers, esophageal erosions, GERD, and conditions–eg, Zollinger-Ellison disease and systemic
mastocytosis in which there is ↑ H2 activity due to blocking of the binding of histamine to H2 receptors, resulting in ↓ intracellular concentration of cAMP and acid secretion by gastric parietal cells Adverse
reactions Diarrhea, headache, fatigue, myalgia, constipation, confusion, agranulocytosis, gynecomastia, impotence, allergic reactions, tachycardia, arrhythmias, interstitial nephritis, etc. See H2 blockers, Histamine receptor antagonists.
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