yeast artificial chromosome

yeast artificial chromosome (YAC),

a yeast chromosome used in recombinant DNA procedures. It can carry large segments of foreign DNA.

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yeast

a general term including unicellular, nucleated, usually rounded fungi that reproduce by budding; some are fermenters of carbohydrates, and a few are pathogenic for animals. See also mastitis.

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yeast artificial chromosome

cloning vectors developed for the cloning of large (200-500 kbp) DNA fragments; YAC libraries permit the cloning of large genes with their flanking regulatory sequences as well as families of contiguous genes. They are difficult to work with and have the further disadvantage that the cloned sequences are unstably retained.

brewer's yeast

Saccharomyces cerevisiae used in brewing beer, making alcoholic liquors, and baking bread. See also dried yeast (below).

dried yeast

dried cells of any suitable strain of Saccharomyces cerevisiae, usually a by-product of the brewing industry; used as a natural source of protein and B-complex vitamins.

yeast two-hybrid system

an experimental technique for identifying genes whose protein product interacts with another particular protein of interest.