YY1


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YY1

A gene on chromosome 14q that encodes a ubiquitous transcription factor belonging to the GLI-Kruppel class of zinc finger proteins, which directs histone deacetylases or histone acetyltransferases to myriad promoters activating or repressing their activity, implicating histone modification in YY1 activity.
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References in periodicals archive ?
An increase in YY1 activity caused by rapamycin could suppress the production of insulin and related hormones, which are necessary for muscles to take up glucose (sugar) for energy and keep blood sugar levels stable.
The first intron of the porcine [beta]-casein gene contained the putative Oct-1, SRY, YY1, C/EBP[beta], AP-1, and retroviral TATA box.
Kim, "Retroposition and Evolution of the DNA-binding Motifs of YY1, YY2, and REX1," Nucleic Acids Research 35 (2007): 3442-52.