Patients were advised tab co-amoxiclav 625mg 8 hourly, tab mefenamic acid 500mg 8 hourly, tab chlorpheniramine maleate 4mg once daily, xylometazoline
nasal spray and liquid paraffine nasal drops 2 drops 8 hourly and regular nasal toilet for 5 days.
Piperacillin + Tazobactum, Nasal Drops- Xylometazoline
hydrochloride, Nasal Drops- Xylometazoline
Oral antibiotic prescribed was co-amoxiclav, vasoconstrictive nasal spray used was Xylometazoline
and local antibiotic ointment prescribed was fucidic acid ointment.
His previous medications oral cetirizine 10 mg/day in morning and hydroxyzine 25 mg/day in evening along with montelukast sodium 10 mg/day along with xylometazoline
nasal drops were continued.
The latest report also states that Novartis containing Xylometazoline
, could cause strophic rhinitis if not used as directed.
After the first five days, a four day course of Xylometazoline
nasal drops was prescribed, followed up with gentle steam inhalation for another week.
Continued use of xylometazoline
for more than 3 days may result in rebound nasal congestion and rhinitis medicamentosa.
Those include mirtazapine, xylometazoline
, fluticasone, paroxetine, pantoprazole, steroids, acetazolamide, and protriptyline.
The alert concerns 12 active ingredients: brompheniramine, chlorphenamine, dextromethorphan, diphenhydramine, ephedrine, guaifenesin, ipecacuanha, phenylephrine, pholcodine, pseudoephedrine, oxymetazoline, and xylometazoline
The results indicated that the potency (pEC50 values) rank order was Dexmedetomidine > Guanabenz > p-aminoclonidine > UK-14304 > Oxymetazoline > Clonidine > Xylometazoline
> Guanfacine > Naphazoline > (-)EPI > [alpha]-methyl-NE > 6-FNE > (-)NE > Deoxy EPI > Dopamine (deoxyNE) > Xylazine > (+)-NE > (-)-Phenylephrine > Isoproterenol.
Other available nasal vasoconstrictors are xylometazoline
(Otrivine), oxymetazoline, ephedrine and phenylephrine.
Jamal reported more dramatic differences in a controlled study of the vasoconstrictor xylometazoline