xanthoma (redirected from Xathoma)

xanthoma /xan·tho·ma/ (zan-tho´mah) a tumor composed of lipid-laden foam cells, which are histiocytes containing cytoplasmic lipid material.

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diabetic xanthoma , xanthoma diabetico´rum eruptive x.

disseminated xanthoma , xanthoma dissemina´tum a rare, normolipoproteinemic form manifested by the development of reddish yellow to brown papules and nodules that may coalesce to form plaques, chiefly involving flexural ureases, the mucous membranes of the mouth and respiratory tract, cornea, sclera, and central nervous system.

eruptive xanthoma , xanthoma erupti´vum a form marked by sudden eruption of crops of small, yellow or yellowish orange papules encircled by an erythematous halo, especially on the buttocks, posterior thighs, and elbows, and caused by high concentrations of plasma triglycerides, especially that associated with uncontrolled diabetes mellitus.

fibrous xanthoma  benign fibrous histiocytoma.

xanthoma mul´tiplex  disseminated x.

planar xanthoma , plane xanthoma, xanthoma pla´num a form manifested as soft yellowish, tannish, or dark red flat macules or slightly elevated plaques, sometimes having a central white area, which may be localized or generalized, often occurring in association with other xanthomas and certain hyperlipoproteinemias.

xanthoma tendino´sum , tendinous xanthoma a form manifested by free movable papules or nodules in the tendons, ligaments, fascia, and periosteum, especially on the backs of the hands, fingers, elbows, knees, and heels, in association with some hyperlipoproteinemias and certain other xanthomas.

xanthoma tubero´sum , tuberous xanthoma a form manifested by groups of flat, or elevated and rounded, yellowish or orangish nodules on the skin over joints, especially on elbows and knees; it may be associated with certain types of hyperlipoproteinemia, biliary cirrhosis, and myxedema.

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xan·tho·ma (zn-thm)

n. pl. xan·tho·mas or xan·tho·ma·ta (-m-t)

A yellowish-orange, lipid-filled nodule or plaque in the skin, often on an eyelid or over a joint.

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xanthoma

[zanthō′mə] pl. xanthomas, xanthomata

Etymology: Gk, xanthos + oma, tumor

a benign fatty fibrous yellowish plaque, nodule, or tumor that develops in the subcutaneous layer of skin, often around tendons. The lesion is characterized by the intracellular accumulation of cholesterol and cholesterol esters. It is associated with high cholesterol and/or triglycerides.

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xanthoma

a papule, nodule or plaque in the skin due to lipid deposits; the color of a xanthoma is usually yellow, but may be brown, reddish, or cream. Microscopically, the lesions show light cells with foamy protoplasm (foam cells, xanthoma cells). They occur most commonly in White Leghorn chickens and rarely in other species.

The formation of xanthomas may indicate an underlying disease, usually related to abnormal metabolism of lipids, including cholesterol. In reptiles they are associated with high cholesterol diets.

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xanthelasma 

A cutaneous deposition of lipid material that appears in the skin of the eyelids, most commonly near the inner canthi. It appears as a yellowish, slightly elevated area. It is a benign and chronic condition that occurs primarily in the elderly. It may be associated with raised blood cholesterol, high-density lipoprotein and triglyceride levels, leading to heart disease or diabetes. Syn. xanthoma; xanthelasma palpebrarum; xanthoma palpebrarum. See corneal arcus; Hollenhorst's plaque.

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xanthoma

Fatty skin growth Dermatology A yellow-orange lipid-filled papule or plaque located on the skin or tendons, which is common in the general population and Pts with DM, and may be ↑ in various 'lipid disorders–eg, lipoprotein lipase deficiency, abetalipoproteinemia, hypercholesterolemia, hypertriglyceridemia