[thrē′ekswī, fôr′ekswī, dob′əleks′-dob′əlwī′]
the designations for abnormal sex chromosome complements in the human male in which there are more than the normal one X and one Y chromosome, resulting in a total of 48, 49, or more chromosomes in each somatic cell. The aberration is a variant of Klinefelter's syndrome. In general, the more X chromosomes there are, the greater the number of congenital defects and the severity of mental retardation in the affected individual. See also Klinefelter's syndrome.
References in periodicals archive ?
48, XXYY, 48, XXXY and 49, XXXXY syndromes: not just variants of Klinefelter syndrome.
Turning our focus to the Red Bull Music Academy arena, you have some of the alumni of Electric Picnic over the 10 years and some of the worlds hottest up and coming acts, from Berlin born Ben Klock closing the show tonight to Manchester's XXXY tomorrow at Midnight with his blend of Garage and House.
The launch event next week sees a special guest appearance from Manchester's XXXY the guy behind the Fabric compilation Elevator Music.
For the remaining cycles of the baseline condition (which ended on cycle 96), XXXY predominated.
Cossey was always feminine in appearance because of an unusual XXXY chromosome pattern, known as Kleinfelter's Syndrome, and by 17 started receiving hormone therapy and living full time as a woman.
see also Greenberg, supra note 6, at 281 (reporting that in addition to forty-six XX/XY, children have been born with chromosomes ranging from XXX, XXY, XXXY, XYY, XYYY, XYYYY to XO).
People who are XXY, XXXY, XXXXY, and XXXXXY are known and are phenotypically male, although not always healthy or fertile.
Even within these classifications, there is a continuum of manifestations, and varieties: for example, the chromosomal combinations can include XXX, XXY, XXXY, XYY, XYYY, XYYYY and XO.
Are those individuals with XO, XXY, XXXY, XYY, XYYY chromosomal sequences to be classified as a new gender type?
Klinefelter syndrome, or 47 XXY, and also in individuals with an extra X chromosome such as XXXY or in those with XY:XXYY mosaicism;