X-chromosome


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Related to X-chromosome: Y-chromosome

X-chromosome

a type of SEX CHROMOSOME containing genes which, when found in a male (XY), always express. Examples of conditions controlled by X-linked genes are HAEMOPHILIA (2 loci), Duchenne muscular dystrophy, colour blindness (2 loci) and a form of diabetes. Compare Y-CHROMOSOME.see SEX LINKAGE.
References in periodicals archive ?
In Caenorhabditis elegans sex-1 is located on the X-chromosome, and it has been confirmed to be a key gene in the negative regulation of transcription of xol-1 (see http://www.
Thus, him-8(e1489) mutants produce a high number of male progeny (approximately 30%) due to increased X-chromosome missegregation that can be easily visualized in the context of the Pxol-1::gfp; him-8(e1489) strain (Figure 5A).
Then, by taking a cell from a non-LIF cell layer and transferring it to a LIF-cell layer, the iPS cell's inactive X-chromosome switched on and became even more like embryonic stem cells.
Lohi X-chromosome also demonstrated high level of stability even in FUdR treated cultures with no fragile sites identified.
By comparing the STR allele pattern of the affected child it is possible to ascertain the presence or absence of the affected X-chromosome allele in the mother and other siblings.
Several X-chromosome located microRNAs were thought to have "important functions in immunity and cancer", said Dr Libert.
As the DMD and BMD both are genetic disorders in which the defective gene is localised on the X-chromosome and the disease is transmitted in X-linked recessive manner thereby primarily affecting the males whereas females being the carriers of the disease are only rarely affected.
Effects of ovarian failure and X-chromosome deletion on body composition and insulin sensitivity in young women.
In modern genetic parlance, X-chromatin evaluation refers to the analysis of X-chromosome only without reference to the Y-chromosome.
Because girls have two X chromosomes, and therefore two copies of every X-linked gene, they are less likely than boys to have symptoms from X-linked genetic diseases because boys don't have a backup copy if an X-chromosome gene has a mutation.
In all 3 cases, the X-chromosome difference stood out even more clearly than the autosomal trisomy.