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Palindrome |
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palindrome [pal′indrōm′] Etymology: Gk, palin + dromos, course a segment of DNA in which identical or almost identical sequences of bases run in opposite directions of the complementary strands. Palindromes are often sites for attack by restriction endonucleases. Palindrome Etymology A word, phrase, number or other sequence of units that can be read the same way in either direction—adjustment of punctuation and spaces between words is permitted
Molecular biology Inverted repeat A sequence of duplex DNA or RNA with dyad symmetry that reads the same in the 5’ to 3’ direction on complementary strands; DNA-binding proteins may recognise palindromes. palindrome literally, something that reads the same backwards as forwards. In nucleic acid biochemistry palindromic sequences of 4 to 10 or more base pairs occur not infrequently. These are of interest because they are recognition sites for cleavage by restriction endonuclease enzymes; responsible for secondary structures in nucleic acids such as the folding of RNA molecules or the hairpin structures found at the termini of the single-stranded DNA genome of parvoviruses. interrupted palindrome restriction enzymes such as BglI recognize sequences which are interrupted palindromes, e.g. GCNNN↓NGGC where N is any nucleotide. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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