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Wolfram Syndrome

   Also found in: Acronyms, Wikipedia 0.01 sec.
Wolfram syndrome
[wool′frəm]
Etymology: D.J. Wolfram, American physician, 20th century
an autosomal-recessive syndrome, first evident in childhood, consisting of diabetes mellitus, diabetes insipidus, optic atrophy, and neural deafness. Also called DIDMOAD syndrome.

Wolfram Syndrome
An autosomal recessive [MIM 222300] condition characterised by diabetes insipidus, non-autoimmune type 1 diabetes mellitus, optic atrophy, sensorineural deafness and further neurological and endocrinological abnormalities. Death occurs prematurely, often from respiratory failure associated with brainstem atrophy


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The researchers were studying the epidemiology of Wolfram syndrome when they first noticed an excess of psychiatric symptoms among relatives of those with the disorder.
 
 
 
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