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Wolff-Chaikoff effect |
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Wolff-Chaikoff effect
[woo͡lf′ chī′kəf] the decreased formation and release of thyroid hormone in the presence of an excess of iodine. Wolff-Chaikoff effect increased blood levels of thyroglobulin bound iodide inhibit further binding of iodide by the thyroid gland.
Wolff-Chaikoff effect Endocrinology An acute adaptive response to high doses of iodine–↑ intracellular iodide blocks the organic-binding and coupling reactions in the thyroid, functionally turning off the thyroid; the WCE used to
prepare the thyroid for surgery. See Hyperthyroidism. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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