Wolff-Chaikoff effect
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Wolff-Chaikoff effect

[woo͡lf′ chī′kəf]

the decreased formation and release of thyroid hormone in the presence of an excess of iodine.

Wolff-Chaikoff effect

increased blood levels of thyroglobulin bound iodide inhibit further binding of iodide by the thyroid gland.

Wolff-Chaikoff effect

Endocrinology An acute adaptive response to high doses of iodine–↑ intracellular iodide blocks the organic-binding and coupling reactions in the thyroid, functionally turning off the thyroid; the WCE used to prepare the thyroid for surgery. See Hyperthyroidism.

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Wolff-Chaikoff effect (redirected from Wolff-Chalkoff effect)

Wolff-Chaikoff effect
(redirected from Wolff-Chalkoff effect)