Whipple's triad

Whipple's triad

the three criteria on which hyperinsulinism due to pancreatic islet-cell disease (most commonly insulinoma) is diagnosed: (1) neuromuscular signs with fasting or exercise, (2) low blood glucose levels associated with clinical signs, and (3) reversal of clinical signs with the administration of glucose.

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Whipple's triad

Endocrinology A triad of features of an insulin-producing tumor: hypoglycemia < 50 mg/dL, CNS and/or vasomotor Sx, relief of Sx by administration of glucose. See Insulinoma.