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wallerian degeneration

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wal·le·ri·an degeneration (w-lîr-n)
n.
The degeneration of a nerve fiber that has been separated from its nutritive center by injury or disease, characterized by segmentation of the myelin and resulting in atrophy and destruction of the axon. Also called orthograde degeneration, secondary degeneration.

wallerian degeneration
[waler′ē·ən]
Etymology: Augustus V. Waller, English physician, 1816-1870; L, degenerare, to degenerate
the fatty degeneration of a nerve fiber after it has been severed from its cell body.

Wallerian degeneration
degeneration of a nerve fiber and its myelin sheath that has been severed from its nutritive source.


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