Waldenstrom macroglobulinemia


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Wal·den·ström mac·ro·glob·u·lin·e·mi·a

(vahld'ĕn-strum),
macroglobulinemia occurring in old people, characterized by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anemia, increased sedimentation rate, and hyperglobulinemia with a narrow peak in γ-globulin or β2-globulin at about 19 S units. The spleen, liver, or lymph nodes are often enlarged with frequent purpura or mucosal bleeding.

Wal·den·ström mac·ro·glob·u·li·ne·mi·a

(vahl'den-strem mak'rō-glob'yū-li-nē'mē-ă)
Macroglobulinemia occurring in old people, characterized by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anemia, an increased sedimentation rate, and hyperglobulinemia with a narrow peak in γ-globulin or β2-globulin at about 19 S units. The spleen, liver, and lymph nodes are often enlarged, and there is frequently purpura or mucosal bleeding.

Waldenström,

Jan G., Swedish physician, 1906–.
Waldenström macroglobulinemia - Synonym(s): hyperglobulinemic purpura; Waldenström purpura; Waldenström syndrome
Waldenström purpura - Synonym(s): Waldenström macroglobulinemia
Waldenström syndrome - Synonym(s): Waldenström macroglobulinemia
Waldenström test - a test for porphyrin in the urine.
References in periodicals archive ?
Chronic immune stimulation and subsequent Waldenstrom macroglobulinemia.
A Monoclonal gammopathy of undetermined significance (MGUS) is the term used to denote the presence of a monoclonal protein (M-protein, myeloma protein, or paraprotein) in persons without evidence of plasma-cell myeloma, Waldenstrom macroglobulinemia, primary amyloidosis, or related disorders.
IgM paraproteinemia is seen in Waldenstrom macroglobulinemia, B-cell lymphoma or lymphoproliferative disorders, monoclonal gammopathy of undermined significance (MGUS), [mu]-heavy chain disease, and IgM myeloma.
MLN0128 (INK128), an investigational oral dual TORC1/2 inhibitor, in patients (pts) with relapsed or refractory multiple myeloma (MM), non-Hodgkin's lymphoma (NHL), or Waldenstrom Macroglobulinemia (WM): results from a phase I dose escalation study
Real World Treatment Patterns, Healthcare Resource Utilization (HRU), and Costs Among Waldenstrom Macroglobulinemia (WM) Patients Initiating Therapy.
Both patients were known to have Waldenstrom macroglobulinemia (IgM-[kappa] type).
Dutcher bodies are PAS-positive, diastase-resistant nuclear pseudoinclusions of eosinophilic cytoplasm found in plasma cells described by Dutcher and Fahey (2) in Waldenstrom macroglobulinemia.
It also reviews key players involved in the therapeutic development for Waldenstrom Macroglobulinemia.
The most common symptoms of patients with [mu] heavy chain disease are those of lymphoproliferative malignancy (chronic lymphatic leukemia, non-Hodgkin lymphoma, Waldenstrom macroglobulinemia, and multiple myeloma).
Because of the high association of this lymphoma with monoclonal gammopathies, and in particular with Waldenstrom macroglobulinemia, its diagnosis should alert the clinician to the possibility of serum paraproteinemia, with or without clinically evident hyperviscosity symptoms.
Waldenstrom Macroglobulinemia Global Clinical Trials Review, H2, 2011" provides data on the Waldenstrom Macroglobulinemia clinical trial scenario.