Witkop syndrome

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tooth-and-nail syn·drome

hypodontia associated with absent or very small nails at birth.
Synonym(s): witkop syndrome

tooth-and-nail syn·drome

hypodontia associated with absent or very small nails at birth.
Synonym(s): witkop syndrome

Witkop syndrome

A rare autosomal dominant ectodermal dysplasia (OMIM:189500) involving the teeth and nails. Most affected individuals have normal hair, sweat glands and ability to tolerate heat, with variable defects in permanent and primary teeth.
 
Molecular pathology
Defects of MSX1, which encodes a homeobox protein involved in epithelial-mesenchymal signalling that has roles in limb-pattern formation and craniofacial development, cause Witkop syndrome.

Witkop syndrome

(wit'kop)
[C.J. Witkop, 20th-cent. Chilean dentist and oral surgeon]
Tooth and nail syndrome .
References in periodicals archive ?
WIKS provides a flexible means for conducting automated tests or quizzes, and saves the teacher the time of grading and recording test results.
Nasdaq has advised the Company that its common stock may be immediately eligible for quotation on the OTC Bulletin Board under the trading symbol WIKS, effective with the opening of business on September 23, 2003, provided a market maker enters a quote for the common stock on that date.