WHO staging system

WHO staging system

AIDS A simplified  AIDS staging system proposed by the WHO Global Programme on AIDS that is flexible enough to be used in different regions, based on 4 groups of clinical conditions that  have prognostic significance and therefore constitute stages, plus an assessment of physical activity performance expressed as a 4-point score; Pts are classified according to the highest stage recorded for either clinical condition or physical activity Categories Asymptomatic; mildly symptomatic; moderately symptomatic; severely symptomatic. See AIDS, HIV-1.
WHO Staging System for HIV Infection
Clinical Stage 1
 
1.  Asymptomatic infection
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2.  Persistent generalized lymphadenopathy
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3.  Acute retroviral infection
 Performance Stage 1: asymptomatic, normal activity
Clinical Stage 2
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4.  Unintentional weight loss < 10% body weight
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5.  Minor mucocutaneous manifestations (e.g., dermatitis, prurigo, fungal nail infections, angular cheilitis)
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6.  Herpes zoster within previous 5 years
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7.  Recurrent upper respiratory tract infections
Performance Stage 2:  symptoms, but nearly fully ambulatory
Clinical Stage 3
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8.  Unintentional weight loss > 10% body weight
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9.  Chronic diarrhea > 1 month
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10.  Prolonged fever > 1 month (constant or intermittent)
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11.  Oral candidiasis
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12.  Oral hairy leukoplakia
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13.  Pulmonary tuberculosis within the previous year
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14.  Severe bacterial infections
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15.  Vulvovaginal candidiasis
Performance Stage 3: in bed > normal but < 50% of normal daytime during the previous month
Clinical Stage 4
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16.  HIV wasting syndrome
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17.Pneumocystis carinii pneumonia
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18.  Toxoplasmosis of the brain
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19.  Crytosporidiosis with diarrhea > 1 month
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20.  Isosporiasis with diarrhea > 1 month
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21.  Cryptococcosis, extrapulmonary
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22.  Cytomegalovirus disease of an organ other than liver, spleen or lymph node
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23.  Herpes simplex virus infection, mucocutaneous
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24.  Progressive multifocal leukoencephalopathy
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25.  Any disseminated endemic mycois (e.g., histoplasmosis)
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26.  Candidiasis of the esophagus, trachea, bronchi, or lung
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27.  Atypical mycobacteriosis, disseminated
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28.  Non-typhoid Salmonella septicemia
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29.  Extrapulmonary tuberculosis
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30.  Lymphoma
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31.  Kaposi's sarcoma
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32.  HIV encephalopathy
http://hivinsite.ucsf.edu/InSite?page=kb-01-01#S4X
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