WHO staging system

WHO staging system

AIDS A simplified  AIDS staging system proposed by the WHO Global Programme on AIDS that is flexible enough to be used in different regions, based on 4 groups of clinical conditions that  have prognostic significance and therefore constitute stages, plus an assessment of physical activity performance expressed as a 4-point score; Pts are classified according to the highest stage recorded for either clinical condition or physical activity Categories Asymptomatic; mildly symptomatic; moderately symptomatic; severely symptomatic. See AIDS, HIV-1.

WHO Staging System for HIV Infection

Clinical Stage 1

 1.  Asymptomatic infection

 2.  Persistent generalized lymphadenopathy

 3.  Acute retroviral infection

 Performance Stage 1: asymptomatic, normal activity

Clinical Stage 2

 4.  Unintentional weight loss < 10% body weight

 5.  Minor mucocutaneous manifestations (e.g., dermatitis, prurigo, fungal nail infections, angular cheilitis)

 6.  Herpes zoster within previous 5 years

 7.  Recurrent upper respiratory tract infections

Performance Stage 2:  symptoms, but nearly fully ambulatory

Clinical Stage 3

 8.  Unintentional weight loss > 10% body weight

 9.  Chronic diarrhea > 1 month

 10.  Prolonged fever > 1 month (constant or intermittent)

 11.  Oral candidiasis

 12.  Oral hairy leukoplakia

 13.  Pulmonary tuberculosis within the previous year

 14.  Severe bacterial infections

 15.  Vulvovaginal candidiasis

Performance Stage 3: in bed > normal but < 50% of normal daytime during the previous month

Clinical Stage 4

 16.  HIV wasting syndrome

17.  Pneumocystis carinii pneumonia

 18.  Toxoplasmosis of the brain

 19.  Crytosporidiosis with diarrhea > 1 month

 20.  Isosporiasis with diarrhea > 1 month

 21.  Cryptococcosis, extrapulmonary

 22.  Cytomegalovirus disease of an organ other than liver, spleen or lymph node

 23.  Herpes simplex virus infection, mucocutaneous

 24.  Progressive multifocal leukoencephalopathy

 25.  Any disseminated endemic mycois (e.g., histoplasmosis)

 26.  Candidiasis of the esophagus, trachea, bronchi, or lung

 27.  Atypical mycobacteriosis, disseminated

 28.  Non-typhoid Salmonella septicemia

 29.  Extrapulmonary tuberculosis

 30.  Lymphoma

 31.  Kaposi's sarcoma

32.  HIV encephalopathy

http://hivinsite.ucsf.edu/InSite?page=kb-01-01#S4X