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WASP Family Protein

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WASP Family Protein
Wiskott-Aldrich Syndrome Protein Family Member 2; Wasf-2. A downstream effector protein [MIM 605875], encoded on 1p36.11-p34.3, which is involved in transmitting signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton; it regulates actin assembly downstream of the cdc42 and phosphatidylinositol bisphosphate signalling pathways


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Physical mechanisms of signal integration by WASP family proteins are elucidated, and virus entry by endocytosis is described.
 
 
 
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