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von Willebrand factor

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von Willebrand factor (vWF)
A protein found in the blood that is involved in the process of blood clotting.
Mentioned in: Von Willebrand Disease
von Willebrand factor
the property of factor VIII necessary for normal platelet function; abbreviated VWF. Called also factor VIIIvwf.
von Willebrand factor
Hematology A large–> 20,000 kD multimeric molecule composed of ± 200 kD monomers, synthesized by vascular endothelium, megakaryocytes and platelets; vWF's hemostatic efficiency is related to multimer size. See Rocket electrophoresis.
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To achieve the proper balance, the body relies on a largely mechanical feedback system that relies on the miniscule forces applied by the circulation system on a molecular "force sensor" known as the A2 domain of the blood clotting protein von Willebrand factor (VWF).
'Bloodcurdling' mystery solved by Asian News International
Von Willebrand Disease The deficiency of von Willebrand factor, also known as a platelet protein, can lead to this disorder in both, men and women.
What Is a Bleeding Disorder and How It Can Be Treated by Serge Dandelin / Health care industry community
Abnormal PFA-100 results were initially found and von Willebrand Factor (vWF) studies indicated a functional discordance (ie functional assays of vWF being significantly reduced as compared to vWF:Ag) suggestive of type 2 von Willebrand Disease (vWD).
Accurate diagnosis of high-affinity vWF-platelet disorders: a case ... by Denholm, Anna; Smith, Mark P.; Patterson, David M. / New Zealand Journal of Medical Laboratory Science
 
 
 
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