cyanocobalamin (redirected from Vitamin B-12)

cyanocobalamin /cy·a·no·co·bal·a·min/ (-ko-bal´ah-min) a cobalamin in which the substituent is a cyanide ion; it is the form of vitamin B12 first isolated and, although an artifact, is used to denote the vitamin; preparations are used to treat vitamin-associated deficiencies, particularly pernicious anemia and other megaloblastic anemias.

---

cy·a·no·co·bal·a·min (s-nk-bl-mn, s-n-)

n.

See vitamin B12.

---

cyanocobalamin

[sī′ənōkōbal′əmin]

Etymology: Gk, kyanos + Ger, kobald, mine goblin

a red crystalline, water-soluble substance that is the common pharmaceutic form of vitamin B₁₂. It is involved in the metabolism of protein, fats, and carbohydrates; normal blood formation; and neural function. It is the first substance containing cobalt found to be vital to life. It cannot be produced synthetically but can be obtained from cultures of Streptomyces griseus. Rich dietary sources are liver, kidney, meats, fish, and dairy products. Deficiency can be caused by the absence of intrinsic factor (produced in the stomach), which is necessary for the absorption of cyanocobalamin from the GI tract. Deficiency can also occur in persons whose diet is strictly vegetarian, thereby excluding meat and dairy sources of the nutrient. Symptoms of deficiency include nervousness, neuritis, numbness and tingling in the hands and feet, poor muscular coordination, and menstrual disturbances. Cyanocobalamin (via injection) is used in the prophylaxis and treatment of pernicious anemia, tropical and nontropical sprue, and other macrocytic and megaloblastic anemias. It is relatively nontoxic, even when administered in amounts greater than those recommended for therapeutic purposes. Also called antipernicious anemia factor, vitamin B₁₂, extrinsic factor. See also intrinsic factor, pernicious anemia.

---

cyanocobalamin [si″ah-no-ko-bal´ah-min]

vitamin B₁₂, a substance having hematopoietic activity found in liver, fish meal, eggs, and other natural sources, or produced from cultures of Streptomyces griseus; it combines with intrinsic factor for absorption and is needed for erythrocyte maturation. Absence of intrinsic factor leads to malabsorption of cyanocobalamin and results in pernicious anemia. Called also extrinsic factor. See also vitamin.

cyanocobalamin Co-57 a radiopharmaceutical used in the schilling test for the diagnosis of pernicious anemia.

---

cyanocobalamin (sīˈ··nōˈ·kō·baˑ·l·mn),

n See vitamin B₁₂.

---

cyanocobalamin (sī´nō´kōbal´min),

n (vitamin B₁₂),
brand names (some): Alpha Redisol, Betalin-12, Cobex;
drug class: Vitamin B₁₂ water-soluble vitamin;
action: needed for adequate nerve functioning, protein and carbohydrate metabolism, normal growth, red blood cell development, and cell reproduction;
uses: vitamin B₁₂ deficiency, pernicious anemia, hemolytic anemia, hemorrhage, and renal and hepatic diseases.

---

cyanocobalamin

vitamin b12.

---

cyanocobalamin

Vitamin B₁₂ A water soluble B vitamin, central to proper CNS function, and carbohydrate, protein and fat metabolism. See Vitamin B_12.

---

Patient discussion about cyanocobalamin.

Q. Can a food rich in vitamin B12 will help for his depression or vitamin B12 pills are always required? Hi all…..having one question related to my friends depression and its relation to vitamin B12, as a medicine given to him by his Doctor. Can a food rich in vitamin B12 will help for his depression or vitamin B12 pills are always required?

A. Yes low level of vitamin B12 is associated with depression. You can complete its deficiency by having good diet which will cover the B12 requirements. What happens that depressed people tend to eat less of healthy food and which reduces the B12. So, it again reduces the capacity to fight against the depression.