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maedi
(redirected from Visna virus)

   Also found in: Wikipedia 0.03 sec.
maedi/visna virus,
a lentivirus that is the causal agent of a type of pneumonia in sheep.

maedi
a chronic pneumonia of sheep caused by a lentivirus, which also causes visna when it invades the brain of sheep. In maedi the characteristic features are a prolonged incubation period of more than 2 years, a progressive pneumonia which lasts for about 6 months, and, at the inevitable death, an abnormally high density and heaviness of the lungs. Called also maedi-visna, Graff-Reinert disease, la bouhite, ovine progressive pneumonia and lymphoid interstitial pneumonia.


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When they applied the LearnCoil program to databases of sequences, the researchers found evidence of coiled coils in fusion proteins associated with a wide variety of disease-causing viruses, including the influenza virus, Moloney murine leukemia virus, HIV, simian immunodeficiency virus, and visna virus.
Like HIV in humans, animal viruses such as feline immunodeficiency virus (FIV) in cats, visna virus in sheep and simian immunodeficiency virus (SIV) in monkeys primarily infect cells of the immune system such as T cells and macrophages.
Visna virus ran second, with HTLV-I and BLV a distant third.
 
 
 
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