vindesine


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vindesine

 [vin´dĕ-sēn]
a synthetic vinca alkaloid derived from vinblastine, administered intravenously as the sulfate salt as an antineoplastic agent in the treatment of acute lymphoblastic leukemia and non–small cell carcinoma.

vin·de·sine

(vin'dĕ-sēn),
Synthetic derivative of vinblastine that shares antineoplastic properties with the latter agent; used to treat childhood lymphocytic leukemia.

vindesine

Eldisine® Oncology An experimental vinca alkaloid used to manage CA, Hodgkin's disease, leukemia, other lymphoproliferative disorders Adverse effects BM toxicity, neuropathy

vindesine

A vinca alkaloid anticancer drug (see CYTOTOXIC DRUGS) used to treat LEUKAEMIA. A brand name is Eldisine.
References in periodicals archive ?
The patient subsequently received treatment with CHOP (cyclophosphamide, clarithromycin lactobionate, vindesine, and dexamethasone) therapy.
Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer.
Neurotoxic Agents by Class Class Medications Bortezomib Cytomib[R], Velcade[R] Platinum compounds Cisplatin (Platinol[R]) Carboplatin (Paraplatin[R]) Oxaliplatin (Eloxatin[R]) Taxanes Paclitaxel (Abraxane[R], Taxol[R]) Docetaxel (Taxotere[R]) Thalidomide, lenalidomide Thalomid[R], REVLIMID[R] Vinca alkaloids Vincristine (Oncovin[R]) Vnblastine Vindesine Vinorelbine (Navelbine[R]) Source: Naleschinski et al.
Invitation to tender: drugs of the l-compositions for treating malignancies (thioguanine, vinblastine, vincristine, vindesine, vinorelbine, etc.
Well known examples include Vinca alkaloids (vincristine, vinblastine, vindesine, vinorelbine), taxanes (paclitaxel, docetaxel), epipodophyllotoxines (etoposide, teniposide), camptothecine and its derivatives (topothecan, irinothecan), and anthracydines (doxorubicin, daunorubicin, epirubicine, idarubicin).
Combination chemotherapy with doxorubicin, bleomycin and vindesine for AIDS-related Kaposi's sarcoma.
Cytotoxic drugs such as 5-fluorouracil, 5-iododeoxyuridine, doxorubicin, and vindesine can be effectively incorporated into VLDL, and the resultant complexes showed effective cytotoxicity to human carcinoma cells.
In 1994, Shimizu (16) reported a case of mediastinal MFH treated preoperatively with cis-platinum, vindesine, and mitomycin C to reduce tumor size, but this regimen failed to have a positive effect.
One patient (20%) was treated with multiple second-line chemotherapeutic agents, including vindesine, mitomycin C, and prednisone.
Randomized study of vinorelbine and cisplatin versus vindesine and cisplatin versus vinorelbine alone in advanced non-small cell lung cancer: Results of a European Multicenter Trial including 612 patients.
Randomized study of vinorelbine and cisplatin versus vindesine and cisplatin versus vinorelbine alone in advanced non-small-cell lung cancer: results of an european multicenter trial including 612 patients.
2] cisplatin (total dosage) plus one of these drugs: etoposide, vinorelbine, vinblastine, and vindesine.