vindesine


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vindesine

 [vin´dĕ-sēn]
a synthetic vinca alkaloid derived from vinblastine, administered intravenously as the sulfate salt as an antineoplastic agent in the treatment of acute lymphoblastic leukemia and non–small cell carcinoma.

vin·de·sine

(vin'dĕ-sēn),
Synthetic derivative of vinblastine that shares antineoplastic properties with the latter agent; used to treat childhood lymphocytic leukemia.

vindesine

Eldisine® Oncology An experimental vinca alkaloid used to manage CA, Hodgkin's disease, leukemia, other lymphoproliferative disorders Adverse effects BM toxicity, neuropathy

vindesine

A vinca alkaloid anticancer drug (see CYTOTOXIC DRUGS) used to treat LEUKAEMIA. A brand name is Eldisine.
References in periodicals archive ?
Invitation to tender: drugs of the l-compositions for treating malignancies (thioguanine, vinblastine, vincristine, vindesine, vinorelbine, etc.
Well known examples include Vinca alkaloids (vincristine, vinblastine, vindesine, vinorelbine), taxanes (paclitaxel, docetaxel), epipodophyllotoxines (etoposide, teniposide), camptothecine and its derivatives (topothecan, irinothecan), and anthracydines (doxorubicin, daunorubicin, epirubicine, idarubicin).
Mersana's proprietary payload platforms include Dolaflexin(TM), an auristatin derivative; Vindeflexin(TM), a vindesine derivative; and Cytoflexin(TM), a tubulysin derivative.
Combination chemotherapy with doxorubicin, bleomycin and vindesine for AIDS-related Kaposi's sarcoma.
One patient (20%) was treated with multiple second-line chemotherapeutic agents, including vindesine, mitomycin C, and prednisone.
Randomized study of vinorelbine and cisplatin versus vindesine and cisplatin versus vinorelbine alone in advanced non-small cell lung cancer: Results of a European Multicenter Trial including 612 patients.
Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer.
2] cisplatin (total dosage) plus one of these drugs: etoposide, vinorelbine, vinblastine, and vindesine.
Name of products Acidum pipemidig Atenolol Albendazol Amineptina Aciclovir Acid clavulanic Astemizole Aztreonam Bacampicillin Budesonide Bitolterol mesylate Bromcriptine masylate Bifonazol Cyclosporin Cefadroxil monohydrat Cefotaxime sodium Cyclopirox olamine Cytarabine Hcl Cetraxate Hcl Cefsulodin sodium Cefoperazone Domperidon Estazolam Fentiazac Isoconazol Ipratropium bromide Ifosfamide Ketoconazol Labetalol Hcl Minoxidil Miconazol Metroprolol tartrat Metrizamide Mianserin Hcl Midazolam malfate Metilmicin SO4 Nadolol Nicardipine Hcl Nor floxacin Oxatomide Piroxicam Praziquantel Procaterol Hcl Prazosin Hcl Sisomicin sulfat Sulprostone Tiemonium metil SO4 Tioconazole Vindesine SO4 Vecuronium bromide
In attempts to improve outcome with more intensive chemotherapy, cyclophosphamide, doxorubicin, vincristine, and prednisone-like regimens, such as methotrexate, doxorubicin, cyclophosphamide, vincristine, bleomycin and prednisone and vindesine, doxorubicin, cyclophosphamide, and prednisone MACOP-B, have been used (30,31) but they have failed to show additional benefit.
Taguchi H, Kinoshita KI, Takatsuki K, et al: An intensive chemotherapy of adult T-cell leukemia/lymphoma CHOP followed by etoposide, vindesine, ranimustine, and mitoxantrone with granulocyte colony-stimulating factor support.
Of the 21 cases, 17 (81%) were treated with multidrug regimens (either CHOP or the combination of doxorubicin, cyclophosphamide, vindesine, bleomycin, and prednisone).