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Amsterdam criteria
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Amsterdam criteria

Oncology Criteria for diagnosing hereditary nonpolyposis colorectal cancer, see there

Amsterdam criteria

Family history: Presence of histologically verified colorectal cancer in ≥ 3 relatives–one of whom is a 1^st-degree relative of the other 2
'Vertical' history: Presence of disease in ≥ 2 successive generations
Age of onset: Age < 50 in > 1 affected relative
Exclusion: Hereditary polyposis syndromes have been excluded

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