hepatic veno-occlusive disease with immunodeficiency

(redirected from VODI)
Also found in: Acronyms.

hepatic veno-occlusive disease with immunodeficiency

An autosomal recessive immune deficiency (OMIM:235550) characterised by severe hypogammaglobulinaemia, combined T- and B-cell immune deficiency, absent lymph node germinal centres, and absent tissue plasma cells; it is associated with hepatic vascular occlusion and fibrosis. 

Molecular pathology
Caused by defects of SB110, which encodes a transcription factor thought to play a role in ribosome formation and in induction of myeloid cell differentiation.
References in periodicals archive ?
VODI is a community healthcare coalition whose members consist of Detroit area healthcare systems (i.
VODI will focus on health disparities associated with diabetes and hypertension in the Conner Creek Community (zip codes 48205 and 48234).
This grant and Ascension Health's leadership in matching the grant money will truly benefit those in our community who are most in need," says Lucille Smith, Executive Director of VODI.