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VIPoma

   Also found in: Wikipedia 0.01 sec.
VIPoma /VIP·oma/ (vĭ-po´mah) an endocrine tumor, usually an islet cell tumor, that produces vasoactive intestinal polypeptide, causing a syndrome of watery diarrhea, hypokalemia, and hypochlorhydria, leading to potentially fatal renal failure. Alternatively, vipoma.
vipoma /vip·oma/ (vĭ-po´mah) VIPoma.
vi·po·ma (v-pm)
n.
An endocrine tumor, usually originating in the pancreas, that produces a vasoactive intestinal polypeptide believed to cause profound cardiovascular and electrolyte changes with vasodilatory hypotension, watery diarrhea, hypokalemia, and dehydration.

VIPoma
[vipō′mə]
a type of pancreatic tumor that causes changes in secretion of vasoactive intestinal polypeptide (VIP). VIP causes dilation of blood vessels throughout the body and secretion of fluid and salt in the intestinal tract, resulting in diarrhea. The VIP effects mimic the symptoms of cholera (severe diarrhea, hypokalemia, and hypochlorhydria) and can result in death from dehydration and subsequent kidney failure if treatment is not begun early. See also vasoactive intestinal polypeptide.

VIPoma
Oncology A VIP–vasoactive intestinal peptide-producing tumor of the pancreas, which is associated with a cholera-like syndrome in absence of gastric hypersecretion. See VIPoma syndrome.


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