urokinase /uro·ki·nase/ (UK) (u″ro-ki´nās) u-plasminogen activator; an enzyme in the urine of humans and other mammals, elaborated by the parenchymal cells of the human kidney and acting as a plasminogen activator. It is used as a therapeutic thrombolytic agent.
urokinase
urokinase (yoor´ōkī´nās),
urokinase
u·ro·ki·nase (y r  -k  n s, -nz)n. An enzyme that catalyzes the conversion of plasminogen to plasmin and is produced in the kidney, excreted in the urine, and used to dissolve blood clots. Also called plasminogen activator. |
urokinase
[yoo͡r′əkī′nās]
an enzyme produced in the kidney and found in urine that is a potent plasminogen activator of the fibrinolytic system. A pharmaceutic preparation of urokinase is administered intravenously in the treatment of pulmonary embolism.
urokinase (yoor´ōkī´nās),
n an enzyme produced in the kidney and found in urine that is a potent plasminogen activator of the fibrinolytic system. A pharmaceutic preparation of urokinase is administered intravenously in the treatment of pulmonary embolism.
urokinase
an enzyme found in the urine of humans and other mammals which is secreted by kidney parenchymal cells and converts plasminogen to plasmin and activates the fibrinolytic system; used as a fibrinolytic agent.
urokinase
A fibrinolytic enzyme involved in extracellular proteolysis; it is more active during cell migration and tissue remodeling, and cleaves fibronectin. See Kringle domain. Cf Streptokinase, Reteplase, tPA.
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