upregulate

upregulate

(ŭp-rĕg′yŭ-lāt)
1. To increase the responsiveness of a cell or organ to a stimulus.
2. To increase the number of receptors on a cell membrane.
References in periodicals archive ?
The carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), another promising tumor suppressor protein, has been shown to upregulate SASH1.
Simultaneously, a signal is sent to nucleus to upregulate production of protein folding components and downregulate other transcription events.
Just by breaking up your sedentary time, we can actually upregulate that process in the body," she added.
2002), relatively few compounds have been reported that can upregulate ABCA1 expression.
Background: Molecular events that cause tumor formation upregulate a number of HOX genes, called switch genes, coding for RNA polymerase II transcription factors.
The big picture here is that viral infections may upregulate, or increase, one or more receptors on the airway cells and make them more sensitive to environmental exposures.
Once infected, pDCs traffic HIV into the T-cell areas of lymphoid tissues, where they generate IFN-[alpha], upregulate IL-12 receptors, and produce HIV.
If you could upregulate [increase] maspin production, it's potentially a new therapeutic direction," comments William Stetler-Stevenson at the National Cancer Institute in Bethesda, Md.
Th2 cells drive the type-2 pathway ("humoral immunity") and upregulate antibody production to fight extracellular organisms; type 2 dominance is credited with tolerance of xenografts and of the fetus during pregnancy.
On the other hand, in our study Juzen-taiho-to did not upregulate the population of CD16-negative CD158a/b-positive cells; it upregulated only CD16-positive CD158a/b-positive cells.
And we found that healthy-weight children are better able to upregulate the neuroelectric processes that underlie error evaluation.
The long-term goal would be to upregulate or boost compensatory factors in patients with mitochondrial disease with the aim to open new avenues for therapy.