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Vulnerable Plaque
(redirected from Unstable Plaque)

   Also found in: Wikipedia 0.01 sec.
Vulnerable Plaque
An atheromatous plaque in an arterial wall, which has abundant macrophages, gobs of lipids and cholesterol, and is usually covered by a thin fibrous cap which may rupture. The repeated cycle of rupture and healing is regarded as the major mechanism of arterial stenosis in atherosclerotic heart disease, myocardial infarction and strokes


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2] has been shown to be a predictor of unstable plaque, myocardial infarction (MI), and ischemic stroke.
These small, unstable plaques are much more likely to rupture and release the cholesterol mass into the bloodstream.
By targeting this key pathway in vascular inflammation, we believe VIA-2291 may have the potential to reduce the major adverse cardiac events that occur as a result of the rupture of unstable plaque.
 
 
 
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